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(1E)-CFI-400437 dihydrochloride

Catalog No. T22288   CAS 1247000-76-5
Synonyms: CFI-400437 dihydrochloride

(1E)-CFI-400437 dihydrochloride (CFI-400437 dihydrochloride) is a selective and potent polo-like kinase 4 (PLK4) inhibitor.

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(1E)-CFI-400437 dihydrochloride Chemical Structure
(1E)-CFI-400437 dihydrochloride, CAS 1247000-76-5
Pack Size Availability Price/USD Quantity
1 mg In stock $ 80.00
5 mg In stock $ 172.00
10 mg In stock $ 263.00
25 mg In stock $ 538.00
50 mg In stock $ 777.00
100 mg In stock $ 1,090.00
500 mg In stock $ 2,170.00
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Purity: 98.36%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description (1E)-CFI-400437 dihydrochloride (CFI-400437 dihydrochloride) is a selective and potent polo-like kinase 4 (PLK4) inhibitor.
Targets&IC50 PLK3:0.6 nM (IC50)
Synonyms CFI-400437 dihydrochloride
Molecular Weight 565.5
Formula C29H30Cl2N6O2
CAS No. 1247000-76-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 5 mM

TargetMolReferences and Literature

1. Suri A , Bailey A W , Tavares M T , et al. Evaluation of Protein Kinase Inhibitors with PLK4 Cross-Over Potential in a Pre-Clinical Model of Cancer[J]. International Journal of Molecular Sciences, 2019, 20(9).

Related compound libraries

This product is contained In the following compound libraries:
Bioactive Compounds Library Max Bioactive Compound Library Kinase Inhibitor Library Inhibitor Library Cell Cycle Compound Library Anti-Cancer Compound Library NO PAINS Compound Library

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Keywords

(1E)-CFI-400437 dihydrochloride 1247000-76-5 Cell Cycle/Checkpoint PLK antiproliferative Inhibitor CFI-400437 Polo-like Kinase (PLK) anticancer cells MCF-7 CFI-400437 dihydrochloride (1E) CFI 400437 dihydrochloride CFI400437 CFI-400437 Dihydrochloride CFI 400437 Dihydrochloride PLK4 CFI400437 Dihydrochloride inhibit CFI 400437 (1E)CFI400437 dihydrochloride inhibitor

 

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