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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | β-Glucuronide-dPBD-PEG5-NH2 is a β-glucuronide-linked pyrrolobenzodiazepine dimer that functions as a proagent for the synthesis of the antibody-drug conjugate (ADC) cIRCR201-dPBD, utilizing a cleavable β-glucuronide linkage. This compound targets and binds to the prenylated antibody, facilitating the controlled release of the drug and thereby mitigating side effects. Furthermore, β-Glucuronide-dPBD-PEG5-NH2 exhibits antitumor properties by inducing apoptosis and arresting the cell cycle [1]. |
Molecular Weight | 1696.66 |
Formula | C78H101N7O35 |
Cas No. | 2246363-68-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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