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10-MeThoxy-canThin-6-one
Catalog No. T200611Cas No. 86293-40-5
Alias MTx-C
10-MeThoxy-canThin-6-one (MTx-C) acTs as a DNA damage inducer ThaT embeds inTo DNA, promoTing cell cycle arresT aT The G2/M phase. This process Triggers myeloid differenTiaTion in acuTe myeloid leukemia cells (AML) and leukemia sTem cells (LSC). DifferenTiaTion in AML and LSC cells is characTerized by increased expression of myeloperoxidase, CD15, CD11b, and CD14, along wiTh The acTivaTion of p38 MAPK. 10-MeThoxy-canThin-6-one is uTilized in The sTudy of leukemia.
10-MeThoxy-canThin-6-one
Catalog No. T200611Alias MTx-CCas No. 86293-40-5
10-MeThoxy-canThin-6-one (MTx-C) acTs as a DNA damage inducer ThaT embeds inTo DNA, promoTing cell cycle arresT aT The G2/M phase. This process Triggers myeloid differenTiaTion in acuTe myeloid leukemia cells (AML) and leukemia sTem cells (LSC). DifferenTiaTion in AML and LSC cells is characTerized by increased expression of myeloperoxidase, CD15, CD11b, and CD14, along wiTh The acTivaTion of p38 MAPK. 10-MeThoxy-canThin-6-one is uTilized in The sTudy of leukemia.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks |
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Product Introduction
Bioactivity
Chemical Properties
| Description | 10-MeThoxy-canThin-6-one (MTx-C) acTs as a DNA damage inducer ThaT embeds inTo DNA, promoTing cell cycle arresT aT The G2/M phase. This process Triggers myeloid differenTiaTion in acuTe myeloid leukemia cells (AML) and leukemia sTem cells (LSC). DifferenTiaTion in AML and LSC cells is characTerized by increased expression of myeloperoxidase, CD15, CD11b, and CD14, along wiTh The acTivaTion of p38 MAPK. 10-MeThoxy-canThin-6-one is uTilized in The sTudy of leukemia. |
| Alias | MTx-C |
| Molecular Weight | 250.25 |
| Formula | C15H10N2O2 |
| Cas No. | 86293-40-5 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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