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2-Desoxy-4-epi-pulchellin

Catalog No. TN2755Cas No. 122872-03-1

2-Desoxy-4-epi-pulchellin has potent in vitro cytotoxicities against the K562, MCF-7, Hela, DU145, U937, H1975, SGC-7901, A549, MOLT-4, and HL60 cell lines with IC50 values ranging from 0.10 to 46.7uM, while it shows significant antiviral (H1N1 and H3N2) activities, it also displays significant antimycobacterial activity (IC50=7.6 uM).

2-Desoxy-4-epi-pulchellin

2-Desoxy-4-epi-pulchellin

Purity: 99.89%
Catalog No. TN2755Cas No. 122872-03-1
2-Desoxy-4-epi-pulchellin has potent in vitro cytotoxicities against the K562, MCF-7, Hela, DU145, U937, H1975, SGC-7901, A549, MOLT-4, and HL60 cell lines with IC50 values ranging from 0.10 to 46.7uM, while it shows significant antiviral (H1N1 and H3N2) activities, it also displays significant antimycobacterial activity (IC50=7.6 uM).
Pack SizePriceAvailabilityQuantity
1 mg$122In Stock
5 mg$372In Stock
10 mg$549In Stock
25 mg$869In Stock
50 mg$1,170In Stock
1 mL x 10 mM (in DMSO)$318In Stock
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Purity:99.89%
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COA HNMR HPLC
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Product Introduction

Bioactivity
Description
2-Desoxy-4-epi-pulchellin has potent in vitro cytotoxicities against the K562, MCF-7, Hela, DU145, U937, H1975, SGC-7901, A549, MOLT-4, and HL60 cell lines with IC50 values ranging from 0.10 to 46.7uM, while it shows significant antiviral (H1N1 and H3N2) activities, it also displays significant antimycobacterial activity (IC50=7.6 uM).
In vitro
Dicarabrol (1), as well as three known sesquiterpenes (2-4), had potent in vitro cytotoxicities against the K562, MCF-7, Hela, DU145, U937, H1975, SGC-7901, A549, MOLT-4, and HL60 cell lines with IC50 values ranging from 0.10 to 46.7 μM, while they showed significant antiviral (H1N1 and H3N2) activities. Furthermore, compounds 1, 3 and 4 displayed significant antimycobacterial activity (IC50 3.7, 6.0, and 7.6 μM, respectively).
Chemical Properties
Molecular Weight250.33
FormulaC15H22O3
Cas No.122872-03-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/ml (219.74 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.9947 mL19.9736 mL39.9473 mL199.7363 mL
5 mM0.7989 mL3.9947 mL7.9895 mL39.9473 mL
10 mM0.3995 mL1.9974 mL3.9947 mL19.9736 mL
20 mM0.1997 mL0.9987 mL1.9974 mL9.9868 mL
50 mM0.0799 mL0.3995 mL0.7989 mL3.9947 mL
100 mM0.0399 mL0.1997 mL0.3995 mL1.9974 mL

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Keywords

2-Desoxy-4-epi-pulchellin2Desoxy4epipulchellininhibit2 Desoxy 4 epi pulchellinInhibitor
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