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3-Carene

🥰Excellent
Catalog No. T10109Cas No. 13466-78-9
Alias Delta-3-Carene

3-Carene(Delta-3-Carene) is a bicyclic monoterpene extracted from western larch and Douglas-fir that acts as a phytofungicide.3-Carene inhibits inflammatory infiltrates and COX-2 overexpression induced by nociceptive stimuli.3-Carene has anti-injury properties and promotes the activity and expression of alkaline phosphatase, an early marker of osteoblast differentiation.

3-Carene

3-Carene

🥰Excellent
Catalog No. T10109Alias Delta-3-CareneCas No. 13466-78-9
3-Carene(Delta-3-Carene) is a bicyclic monoterpene extracted from western larch and Douglas-fir that acts as a phytofungicide.3-Carene inhibits inflammatory infiltrates and COX-2 overexpression induced by nociceptive stimuli.3-Carene has anti-injury properties and promotes the activity and expression of alkaline phosphatase, an early marker of osteoblast differentiation.
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100 mg28 €In Stock
500 mg64 €In Stock
1 g93 €In Stock
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Product Introduction

Bioactivity
Description
3-Carene(Delta-3-Carene) is a bicyclic monoterpene extracted from western larch and Douglas-fir that acts as a phytofungicide.3-Carene inhibits inflammatory infiltrates and COX-2 overexpression induced by nociceptive stimuli.3-Carene has anti-injury properties and promotes the activity and expression of alkaline phosphatase, an early marker of osteoblast differentiation.
In vitro
Rat alveolar macrophages were incubated with the monoterpene 3-Carene (0, 0.005, 0.05, 0.5, and 5.0 μM; 75 min; Rat alveolar macrophages) in culture medium for 75 min. A dose-dependent relationship was found between the cell viability and the 3-Carene concentration. At 5.0 μM 3-Carene, 98% of the AM were dead. The phagocytosis of heat-killed yeast particles was significantly decreased and the attachment of particles to the cell surface significantly increased at 0.5 μM 3-Carene. Electron microscopy showed that about 50% of the AM lacked or had very few surface protrusions after incubation in 0.5 μM 3-Carene. Thus, 3-Carene seemed to affect mainly the engulfment of particles. Surfactant, 0.5 mg/ml as Curosurf, added to the incubation medium, did not affect the AM reaction to 3-Carene exposure.[1]
AliasDelta-3-Carene
Chemical Properties
Molecular Weight136.23
FormulaC10H16
Cas No.13466-78-9
SmilesCC1=CCC2C(C1)C2(C)C
Relative Density.0.857 g/cm3 at 25℃ (lit.)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (367.03 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM7.3405 mL36.7026 mL73.4053 mL367.0264 mL
5 mM1.4681 mL7.3405 mL14.6811 mL73.4053 mL
10 mM0.7341 mL3.6703 mL7.3405 mL36.7026 mL
20 mM0.3670 mL1.8351 mL3.6703 mL18.3513 mL
50 mM0.1468 mL0.7341 mL1.4681 mL7.3405 mL
100 mM0.0734 mL0.3670 mL0.7341 mL3.6703 mL

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