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4'-Methoxyresveratrol

Catalog No. T5716 CAS 33626-08-3

Synonyms: 4'-O-Methylresveratrol, 白藜芦醇-4'-甲醚

4'-Methoxyresveratrol is a natural product form the roots of Rheum palmatum L,has significant hypoglycemic, anti-inflammatory, and antioxidant effects.4'-Methoxyresveratrol alleviates AGE-induced inflammation through suppressing RAGE-mediated MAPK/NF-κB signaling pathway and NLRP3 inflammasome activation.

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4'-Methoxyresveratrol, CAS 33626-08-3

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Purity: 98%

Biological Description

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Description

In vitro

4'-Methoxyresveratrol significantly abated the activation of NOD-like receptor pyrin domain containing 3 (NLRP3) inflammasome including NLRP3 and cleaved caspase-1 and reduced the secretion of mature IL-1β. The anti-inflammatory effect of 4'-Methoxyresveratrol is mainly through suppressing RAGE-mediated MAPK/NF-κB signaling pathway and NLRP3 inflammasome activation. 4'-Methoxyresveratrol could be a novel therapeutic agent for inflammation-related diseases.

Synonyms	4'-O-Methylresveratrol, 白藜芦醇-4'-甲醚
Molecular Weight	242.274
Formula	C15H14O3
CAS No.	33626-08-3

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 48 mg/mL (198.13 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Wenzhe Y , Mengru T , Yueliang Z , et al. 4′-Methoxyresveratrol Alleviated AGE-Induced Inflammation via RAGE-Mediated NF-κB and NLRP3 Inflammasome Pathway[J]. Molecules, 2018, 23(6):1447-.

Related compound libraries

This product is contained In the following compound libraries：

Traditional Chinese Medicine Monomer Library Tibetan medicine Compound Library Inhibitor Library Polyphenolic Natural Product Library Natural Product Library for HTS Oxidation-Reduction Compound Library Immunology/Inflammation Compound Library Kinase Inhibitor Library NF-κB Signaling Compound Library Anti-Inflammatory Traditional Chinese Medicine Compound Library

Related Products

Related compounds with same targets

4'-Methoxyresveratrol FPS-ZM1 Azeliragon Ipriflavone

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Keywords

4'-Methoxyresveratrol 33626-08-3 其他 advanced glycation end products Inhibitor 4' Methoxyresveratrol 4'-O-Methylresveratrol 4'Methoxyresveratrol inhibit inhibitor

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