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4-Thiouridine

🥰Excellent
Catalog No. T35648Cas No. 13957-31-8

4-Thiouridine (4-SU) is a photoactivatable ribonucleoside analog that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labeling. The crosslinking thio moiety is attached directly to the nucleotide base, thus 4-SU

4-Thiouridine

4-Thiouridine

🥰Excellent
Purity: 99.89%
Catalog No. T35648Cas No. 13957-31-8
4-Thiouridine (4-SU) is a photoactivatable ribonucleoside analog that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labeling. The crosslinking thio moiety is attached directly to the nucleotide base, thus 4-SU
Pack SizePriceAvailabilityQuantity
5 mg$40 In Stock
10 mg$68 In Stock
25 mg$129 In Stock
50 mg$228 In Stock
100 mg$388 In Stock
200 mg$525 In Stock
1 mL x 10 mM (in DMSO)$44 In Stock
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Purity:99.89%
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COA HPLC HNMR
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Product Introduction

Bioactivity
Description
4-Thiouridine (4-SU) is a photoactivatable ribonucleoside analog that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labeling. The crosslinking thio moiety is attached directly to the nucleotide base, thus 4-SU
Chemical Properties
Molecular Weight260.27
FormulaC9H12N2O5S
Cas No.13957-31-8
SmilesOC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=S)[nH]c1=O
Relative Density.1.72 g/cm3 (Predicted)
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 10 mg/mL (38.42 mM), Sonication is recommended.
PBS (pH 7.2): 5 mg/mL (19.21 mM), Sonication is recommended.
Ethanol: 2 mg/mL (7.68 mM), Sonication is recommended.
DMF: 10 mg/mL (38.42 mM), Sonication is recommended.
H2O: 20 mg/mL (76.84 mM), Sonication is recommended.
Solution Preparation Table
PBS (pH 7.2)/DMSO/DMF/H2O
1mg5mg10mg50mg
10 mM0.3842 mL1.9211 mL3.8422 mL19.2108 mL
DMSO/DMF/H2O
1mg5mg10mg50mg
20 mM0.1921 mL0.9605 mL1.9211 mL9.6054 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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2 Enter the in vivo formulation:
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Keywords

rRNA synthesisRNAribonucleoside analognucleolar stressmRNAlabelInhibitorinhibit4-Thiouridine4Thiouridine4 Thiouridine
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