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4-Thiouridine

🥰Excellent
Catalog No. T35648Cas No. 13957-31-8

4-Thiouridine (4-SU) is a photoactivatable ribonucleoside analog that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labeling. The crosslinking thio moiety is attached directly to the nucleotide base, thus 4-SU

4-Thiouridine

4-Thiouridine

🥰Excellent
Purity: 99.89%
Catalog No. T35648Cas No. 13957-31-8
4-Thiouridine (4-SU) is a photoactivatable ribonucleoside analog that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labeling. The crosslinking thio moiety is attached directly to the nucleotide base, thus 4-SU
Pack SizePriceAvailabilityQuantity
5 mg$40 In Stock
10 mg$68 In Stock
25 mg$129 In Stock
50 mg$228 In Stock
100 mg$388 In Stock
200 mg$525 In Stock
1 mL x 10 mM (in DMSO)$44 In Stock
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Purity:99.89%
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COA HNMR HPLC LCMS
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Product Introduction

Bioactivity
Description
4-Thiouridine (4-SU) is a photoactivatable ribonucleoside analog that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labeling. The crosslinking thio moiety is attached directly to the nucleotide base, thus 4-SU
Chemical Properties
Molecular Weight260.27
FormulaC9H12N2O5S
Cas No.13957-31-8
SmilesOC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=S)[nH]c1=O
Relative Density.1.72 g/cm3 (Predicted)
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 10 mg/mL (38.42 mM), Sonication is recommended.
PBS (pH 7.2): 5 mg/mL (19.21 mM), Sonication is recommended.
Ethanol: 2 mg/mL (7.68 mM), Sonication is recommended.
DMF: 10 mg/mL (38.42 mM), Sonication is recommended.
H2O: 20 mg/mL (76.84 mM), Sonication is recommended.
Solution Preparation Table
PBS (pH 7.2)/DMSO/DMF/H2O
1mg5mg10mg50mg
10 mM0.3842 mL1.9211 mL3.8422 mL19.2108 mL
DMSO/DMF/H2O
1mg5mg10mg50mg
20 mM0.1921 mL0.9605 mL1.9211 mL9.6054 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

rRNA synthesisRNAribonucleoside analognucleolar stressmRNAlabelInhibitorinhibit4-Thiouridine4Thiouridine4 Thiouridine
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