Powder: -20°C for 3 years
In solvent: -80°C for 2 years
4beta-Hydroxywithanolide E(4bHWE) can inhibit the growth of colon cancer monolayer and spheroid cultures, it assert its anti-tumor activity in carcinogenic progression and develop into a dietary chemopreventive agent, it affects alternative splicing by modulating splicing factors and histone modifications.4bHWE is a useful natural anti-inflammatory compound to attenuate progression of diabetes and obesity, it decreases inflammatory responses by inhibiting the NF-κB signaling in diabetic mouse adipose tissue, it also can improve impaired glucose tolerance.
Description | 4beta-Hydroxywithanolide E(4bHWE) can inhibit the growth of colon cancer monolayer and spheroid cultures, it assert its anti-tumor activity in carcinogenic progression and develop into a dietary chemopreventive agent, it affects alternative splicing by modulating splicing factors and histone modifications.4bHWE is a useful natural anti-inflammatory compound to attenuate progression of diabetes and obesity, it decreases inflammatory responses by inhibiting the NF-κB signaling in diabetic mouse adipose tissue, it also can improve impaired glucose tolerance. |
Molecular Weight | 502.604 |
Formula | C28H38O8 |
CAS No. | 54334-04-2 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
( < 1 mg/ml refers to the product slightly soluble or insoluble )
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4beta-Hydroxywithanolide E 54334-04-2 Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Immunology/Inflammation Metabolism Neuroscience NF-Κb COX NF-κB PARP HSP 4betaHydroxywithanolide E 4beta Hydroxywithanolide E Inhibitor inhibitor inhibit