Aurora kinase inhibitor-3

Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR.

Catalog No. T5524Cas No. 879127-16-9

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Purity:98.91%

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Aurora kinase inhibitor-3

Catalog No. T5524Cas No. 879127-16-9

Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR.

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Pack Size	Price	Availability
1 mg	$43	In Stock
5 mg	$119	In Stock
10 mg	$188	In Stock
25 mg	$316	In Stock
50 mg	$449	In Stock
100 mg	$592	In Stock
200 mg	$828	In Stock
1 mL x 10 mM (in DMSO)	$136	In Stock

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Product Introduction

Bioactivity

Description	Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR.
Targets&IC50	Aurora A:42 nM
Alias	Aurora Kinase Inhibitor III

Chemical Properties

Molecular Weight	413.4
Formula	C₂₁H₁₈F₃N₅O
Cas No.	879127-16-9

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 50 mg/mL (120.9 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4190 mL	12.0948 mL	24.1896 mL	120.9482 mL
5 mM	0.4838 mL	2.4190 mL	4.8379 mL	24.1896 mL
10 mM	0.2419 mL	1.2095 mL	2.4190 mL	12.0948 mL
20 mM	0.1209 mL	0.6047 mL	1.2095 mL	6.0474 mL
50 mM	0.0484 mL	0.2419 mL	0.4838 mL	2.4190 mL
100 mM	0.0242 mL	0.1209 mL	0.2419 mL	1.2095 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

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mix well and clarify

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