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Azido-PEG3-Val-Cit-PAB-PNP is a cleavable 3-unit PEG ADC linker used for synthesizing antibody-drug conjugates (ADCs) [1] and also functions as a PEG-based PROTAC linker for PROTAC synthesis [2].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $86 | 5 days |
Description | Azido-PEG3-Val-Cit-PAB-PNP is a cleavable 3-unit PEG ADC linker used for synthesizing antibody-drug conjugates (ADCs) [1] and also functions as a PEG-based PROTAC linker for PROTAC synthesis [2]. |
In vitro | ADCs consist of an antibody attached to an ADC cytotoxin via an ADC linker[1]. PROTACs feature two ligands joined by a linker—one for an E3 ubiquitin ligase and the other for the target protein, utilizing the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
Molecular Weight | 773.801 |
Formula | C34H47N9O12 |
Cas No. | 2055047-18-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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