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Azido-PEG4-hydrazide

Catalog No. T14450Cas No. 2170240-96-5

Azido-PEG4-hydrazide is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.

Azido-PEG4-hydrazide

Azido-PEG4-hydrazide

Purity: 99.95%
Catalog No. T14450Cas No. 2170240-96-5
Azido-PEG4-hydrazide is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.
Pack SizePriceAvailabilityQuantity
2 mg$30In Stock
5 mg$47In Stock
10 mg$68In Stock
25 mg$112In Stock
50 mg$163In Stock
100 mg$247In Stock
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Purity:99.95%
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Product Introduction

Bioactivity
Description
Azido-PEG4-hydrazide is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.
In vitro
PROTAC contains two different ligands linked by a linker; one is a ligand for the E3 ubiquitin ligase and the other is a ligand for the target protein. PROTAC utilizes the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1].
Chemical Properties
Molecular Weight305.33
FormulaC11H23N5O5
Cas No.2170240-96-5
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 80 mg/mL (262.01 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.2751 mL16.3757 mL32.7514 mL163.7572 mL
5 mM0.6550 mL3.2751 mL6.5503 mL32.7514 mL
10 mM0.3275 mL1.6376 mL3.2751 mL16.3757 mL
20 mM0.1638 mL0.8188 mL1.6376 mL8.1879 mL
50 mM0.0655 mL0.3275 mL0.6550 mL3.2751 mL
100 mM0.0328 mL0.1638 mL0.3275 mL1.6376 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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g
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2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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