Shopping Cart
- Remove All
Your shopping cart is currently empty
BB-78485
🥰Excellent
Catalog No. T26748Cas No. 207732-11-4
Alias BB78485, BB 78485
BB-78485 is a potent small molecule inhibitor of LpxC metalloenzymes with antibacterial activity. The IC50 value of BB-78485 against LpxC is 160 nM. BB-78485 can be used for the study of Gram-negative bacterial infections.
BB-78485
🥰Excellent
Purity: 99.49%
Catalog No. T26748Alias BB78485, BB 78485Cas No. 207732-11-4
BB-78485 is a potent small molecule inhibitor of LpxC metalloenzymes with antibacterial activity. The IC50 value of BB-78485 against LpxC is 160 nM. BB-78485 can be used for the study of Gram-negative bacterial infections.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $328 | In Stock | |
| 5 mg | $783 | In Stock | |
| 10 mg | $1,080 | In Stock | |
| 25 mg | $1,570 | In Stock | |
| 50 mg | $1,970 | In Stock | |
| 100 mg | $2,480 | In Stock | |
| 500 mg | $4,910 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreSelect Batch
Purity:99.49%
ee:100%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | BB-78485 is a potent small molecule inhibitor of LpxC metalloenzymes with antibacterial activity. The IC50 value of BB-78485 against LpxC is 160 nM. BB-78485 can be used for the study of Gram-negative bacterial infections. |
| Targets&IC50 | LpxC:160 nM |
| In vitro | BB-78485 can inhibit LpxC with an IC50 value of 160 nM[1].BB-78485 is effective against D21 and D22 (lpxC101), with MIC values of 2 μg/mL and 0.016 μg/mL, respectively[1].The MIC values of BB-78485 against Enterobacteriaceae, Serratia marcescens, Morganella morganii, Moraxella catarrhalis, Haemophilus influenzae, and Burkholderia cepacia range from 1 μg/mL to 32 μg/mL[1]. |
| Alias | BB78485, BB 78485 |
| Molecular Weight | 420.48 |
| Formula | C23H20N2O4S |
| Cas No. | 207732-11-4 |
| Smiles | S(N[C@H](CC1=CC2=C(C=C1)C=CC=C2)C(NO)=O)(=O)(=O)C3=CC4=C(C=C3)C=CC=C4 |
| Relative Density. | 1.375 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy BB-78485 | purchase BB-78485 | BB-78485 cost | order BB-78485 | BB-78485 chemical structure | BB-78485 in vitro | BB-78485 formula | BB-78485 molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.