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CPI-455 HCl

Catalog No. T22299Cas No. 2095432-28-1

CPI-455 is a specific KDM5 inhibitor with IC50 value of 10 ± 1 nM for full-length KDM5A in enzymatic assays, elevating global levels of H3K4 trimethylation (H3K4me3) and decreased the number of DTPs in multiple cancer cell line models treated with targeted agents or standard chemotherapy.

CPI-455 HCl

CPI-455 HCl

Catalog No. T22299Cas No. 2095432-28-1
CPI-455 is a specific KDM5 inhibitor with IC50 value of 10 ± 1 nM for full-length KDM5A in enzymatic assays, elevating global levels of H3K4 trimethylation (H3K4me3) and decreased the number of DTPs in multiple cancer cell line models treated with targeted agents or standard chemotherapy.
Pack SizePriceAvailabilityQuantity
25 mg$1,5201-2 weeks
50 mg$1,9801-2 weeks
100 mg$2,5001-2 weeks
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Product Introduction

Bioactivity
Description
CPI-455 is a specific KDM5 inhibitor with IC50 value of 10 ± 1 nM for full-length KDM5A in enzymatic assays, elevating global levels of H3K4 trimethylation (H3K4me3) and decreased the number of DTPs in multiple cancer cell line models treated with target
Targets&IC50
KDM5A:10 nM
Chemical Properties
Molecular Weight314.77
FormulaC16H15ClN4O
Cas No.2095432-28-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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