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Tranylcypromine hemisulfate

Catalog No. T7942Cas No. 13492-01-8
Alias Tranylcypromine Sulfate, Tranylcypromine (hemisulfate)

Tranylcypromine hemisulfate (Tranylcypromine Sulfate) is an inhibitor of monoamine oxidase (MAO) and lysine-specific demethylase 1 (LSD1) with a rapid onset of activity.

Tranylcypromine hemisulfate

Tranylcypromine hemisulfate

Purity: 99.94%
Catalog No. T7942Alias Tranylcypromine Sulfate, Tranylcypromine (hemisulfate)Cas No. 13492-01-8
Tranylcypromine hemisulfate (Tranylcypromine Sulfate) is an inhibitor of monoamine oxidase (MAO) and lysine-specific demethylase 1 (LSD1) with a rapid onset of activity.
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100 mg$48In Stock
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Purity:99.94%
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Product Introduction

Bioactivity
Description
Tranylcypromine hemisulfate (Tranylcypromine Sulfate) is an inhibitor of monoamine oxidase (MAO) and lysine-specific demethylase 1 (LSD1) with a rapid onset of activity.
In vivo
Tranylcypromine-induced transcriptional and epigenetic regulation modulated RGC survival via the promotion of p38 MAPKγ activity. Therefore, pharmacologic treatments that suppress LSD1 activity may be a novel therapeutic strategy that can be used to treat neurodegenerative diseases[1].
Animal Research
The authors evaluated whether tranylcypromine contributes to neuronal survival following stress-induced damage using primary cultured rat RGCs and in vivo N-methyl-D-aspartate (NMDA)-induced excitotoxicity.?Additionally, the molecules associated with tranylcypromine treatment were assessed by microarray and immunoblot analysis[1].
AliasTranylcypromine Sulfate, Tranylcypromine (hemisulfate)
Chemical Properties
Molecular Weight182.23
FormulaC9H11N 1/2H2SO4
Cas No.13492-01-8
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 10 mg/mL (54.8 mM), Sonication is recommended.
DMSO: 3.33 mg/mL (18 mM), Sonication is recommended.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM5.4876 mL27.4379 mL54.8757 mL274.3785 mL
5 mM1.0975 mL5.4876 mL10.9751 mL54.8757 mL
10 mM0.5488 mL2.7438 mL5.4876 mL27.4379 mL
H2O
1mg5mg10mg50mg
20 mM0.2744 mL1.3719 mL2.7438 mL13.7189 mL
50 mM0.1098 mL0.5488 mL1.0975 mL5.4876 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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