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AS8351

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Purity:99.80%

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COA HNMR HPLC

AS8351

Catalog No. T4100Cas No. 796-42-9

AS8351 (NSC51355) is a histone demethylase inhibitor. It has been used in combination with CHIR99021, A 83-01, BIX01294, SC-1, Y-27632, OAC2, SU 16f, and JNJ-10198409 to induce reprogramming of human fetal lung fibroblasts into functional cardiomyocytes.

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Pack Size	Price	Availability
5 mg	$43	In Stock
10 mg	$64	In Stock
25 mg	$118	In Stock
50 mg	$198	In Stock
100 mg	$369	In Stock
200 mg	$479	In Stock
500 mg	$785	In Stock
1 mL x 10 mM (in DMSO)	$47	In Stock

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Product Introduction

Bioactivity

Description	AS8351 (NSC51355) is a histone demethylase inhibitor. It has been used in combination with CHIR99021, A 83-01, BIX01294, SC-1, Y-27632, OAC2, SU 16f, and JNJ-10198409 to induce reprogramming of human fetal lung fibroblasts into functional cardiomyocytes.
Alias	NSC51355, AS-8351, AS 8351

Chemical Properties

Molecular Weight	291.3
Formula	C17H13N3O2
Cas No.	796-42-9

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (171.64 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.4329 mL	17.1644 mL	34.3289 mL	171.6444 mL
5 mM	0.6866 mL	3.4329 mL	6.8658 mL	34.3289 mL
10 mM	0.3433 mL	1.7164 mL	3.4329 mL	17.1644 mL
20 mM	0.1716 mL	0.8582 mL	1.7164 mL	8.5822 mL
50 mM	0.0687 mL	0.3433 mL	0.6866 mL	3.4329 mL
100 mM	0.0343 mL	0.1716 mL	0.3433 mL	1.7164 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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