store at low temperature,keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Durlobactam sodium salt (ETX2514 sodium salt) is an inhibitor of β-lactamase with IC50 values of 4 nM, 14 nM, and 190 nM for Class A KPC-2, Class C AmpC, and Class D OXA-24, respectively. Durlobactam sodium salt can be used in studies about drug-resistant Gram-negative bacteria including Acinetobacter baumannii.
Pack Size | Availability | Price/USD | Quantity |
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1 mg | In stock | $ 390.00
$ 312.00
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2 mg | In stock | $ 586.00
$ 468.80
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5 mg | In stock | $ 896.00
$ 716.80
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10 mg | In stock | $ 1,316.00
$ 1,052.80
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25 mg | In stock | $ 1,974.00
$ 1,579.20
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50 mg | In stock | $ 2,760.00
$ 2,208.00
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Description | Durlobactam sodium salt (ETX2514 sodium salt) is an inhibitor of β-lactamase with IC50 values of 4 nM, 14 nM, and 190 nM for Class A KPC-2, Class C AmpC, and Class D OXA-24, respectively. Durlobactam sodium salt can be used in studies about drug-resistant Gram-negative bacteria including Acinetobacter baumannii. |
Targets&IC50 | Class C AmpC:14 nM , Class D OXA-24:190 nM , Class A KPC-2:4 nM |
In vitro | Durlobactam sodium salt exhibited antibacterial activity against Enterobacteriaceae including E. coli, Klebsiella pneumoniae, Enterobacter cloacae, Stenotrophomonas maltophilia and Citrobacter species. Durlobactam sodium salt was also active against colistin-resistant E. coli isolates bearing the mcr-1 plasmid[1]. |
In vivo | Sulbactam–Durlobactam in thigh and lung murine infection models showed a dose-dependent reduction in MDR A. baumannii bacterial counts[1]. |
Synonyms | ETX2514 sodium salt |
Molecular Weight | 299.23 |
Formula | C8H10N3NaO6S |
CAS No. | 1467157-21-6 |
store at low temperature,keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 2.5 mg/mL (8.35 mM), Sonification is recommended
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Durlobactam sodium salt 1467157-21-6 Microbiology/Virology Antibacterial ETX-2514 ETX2514 sodium salt ETX 2514 Durlobactam sodium inhibitor inhibit