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EMCS

🥰Excellent
Catalog No. T14061Cas No. 55750-63-5
Alias 6-Maleimidohexanoic acid N-hydroxysuccinimide ester

EMCS (6-Maleimidohexanoic acid N-hydroxysuccinimide ester) is a heterobifunctional crosslinking agent, which is a compound for the preparation of hapten conjugate and enzyme immune conjugate, and an effective protective group in antibody drug conjugate.

EMCS

EMCS

🥰Excellent
Purity: 99.88%
Catalog No. T14061Alias 6-Maleimidohexanoic acid N-hydroxysuccinimide esterCas No. 55750-63-5
EMCS (6-Maleimidohexanoic acid N-hydroxysuccinimide ester) is a heterobifunctional crosslinking agent, which is a compound for the preparation of hapten conjugate and enzyme immune conjugate, and an effective protective group in antibody drug conjugate.
Pack SizePriceAvailabilityQuantity
25 mg$46In Stock
50 mg$64In Stock
100 mg$90In Stock
500 mg$213In Stock
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Purity:99.88%
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Product Introduction

Bioactivity
Description
EMCS (6-Maleimidohexanoic acid N-hydroxysuccinimide ester) is a heterobifunctional crosslinking agent, which is a compound for the preparation of hapten conjugate and enzyme immune conjugate, and an effective protective group in antibody drug conjugate.
In vitro
The peptides are first coupled with 6-Maleimidohexanoic acid N-hydroxysuccinimide ester, and then they are conjugated to the luciferase gene-containing Adenovirus vector as the carrier. [1]
Alias6-Maleimidohexanoic acid N-hydroxysuccinimide ester
Chemical Properties
Molecular Weight308.29
FormulaC14H16N2O6
Cas No.55750-63-5
SmilesO(C(CCCCCN1C(=O)C=CC1=O)=O)N2C(=O)CCC2=O
Relative Density.1.40 g/cm3 (Predicted)
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (145.97 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.2437 mL16.2185 mL32.4370 mL162.1850 mL
5 mM0.6487 mL3.2437 mL6.4874 mL32.4370 mL
10 mM0.3244 mL1.6218 mL3.2437 mL16.2185 mL
20 mM0.1622 mL0.8109 mL1.6218 mL8.1092 mL
50 mM0.0649 mL0.3244 mL0.6487 mL3.2437 mL
100 mM0.0324 mL0.1622 mL0.3244 mL1.6218 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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