Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ERD-308 induces <95% of ER degradation at concentrations as low as 5 nM in both cell lines (DC50 (concentration causing 50% of protein degradation) of 0.17 nM and 0.43 nM in MCF-7 and T47D ER+ cells, respectively).ERD-308 is a highly potent PROTAC degrader of estrogen receptor (ER) for ER positive breast cancer treatment.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | Inquiry | $ 913.00 | |
50 mg | Inquiry | $ 1,650.00 | |
100 mg | Inquiry | $ 2,650.00 |
Description | ERD-308 induces >95% of ER degradation at concentrations as low as 5 nM in both cell lines (DC50 (concentration causing 50% of protein degradation) of 0.17 nM and 0.43 nM in MCF-7 and T47D ER+ cells, respectively).ERD-308 is a highly potent PROTAC degrader of estrogen receptor (ER) for ER positive breast cancer treatment. |
Targets&IC50 | ER (T47D cells):, DC50: 0.17 nM , ER (MCF-7 cells):0.43 nM |
Molecular Weight | 1004.26 |
Formula | C55H65N5O9S2 |
CAS No. | 2320561-35-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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ERD-308 2320561-35-9 Others ERD 308 ERD308 inhibitor inhibit