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Etiprednol dicloacetate
Catalog No. T31719Cas No. 199331-40-3
Alias BNP-166, BNP166, BNP 166
Etiprednol dicloacetate (BNP-166) is a corticosteroid with anti-inflammatory activity.Etiprednol dicloacetate inhibits the accumulation of eosinophils and can be used in the study of inflammatory airway diseases such as asthma and in the treatment of Crohn's disease.
Etiprednol dicloacetate
Catalog No. T31719Alias BNP-166, BNP166, BNP 166Cas No. 199331-40-3
Etiprednol dicloacetate (BNP-166) is a corticosteroid with anti-inflammatory activity.Etiprednol dicloacetate inhibits the accumulation of eosinophils and can be used in the study of inflammatory airway diseases such as asthma and in the treatment of Crohn's disease.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $112 | In Stock | |
| 5 mg | $260 | In Stock | |
| 10 mg | $390 | In Stock | |
| 25 mg | $653 | In Stock | |
| 50 mg | $928 | In Stock | |
| 100 mg | $1,260 | In Stock |
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Purity:99.43%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Etiprednol dicloacetate (BNP-166) is a corticosteroid with anti-inflammatory activity.Etiprednol dicloacetate inhibits the accumulation of eosinophils and can be used in the study of inflammatory airway diseases such as asthma and in the treatment of Crohn's disease. |
| In vitro | Etiprednol dicloacetate (1 nM-1 μM) inhibits LPS-induced TNF-α production in human blood.[1] |
| In vivo | Etiprednol dicloacetate (0-100 μg/kg; intranasal inhalation) reduces peribronchial eosinophilia in the lungs of allergen-sensitized and challenged rats.[1] It is well-tolerated in rats and dogs at doses of up to 20 mg/kg administered orally over 28 days.[2] Etiprednol dicloacetate (0.1 μg/kg; intranasal inhalation) inhibits eosinophil accumulation in rats induced by antigen exposure.[3] |
| Alias | BNP-166, BNP166, BNP 166 |
| Molecular Weight | 485.4 |
| Formula | C24H30Cl2O6 |
| Cas No. | 199331-40-3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/mL (113.31 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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