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FT895

Catalog No. T11329 CAS 2225728-57-2

FT895 is a selective and potent HDAC11 inhibitor with antifungal and antitumor activity that inhibits HDAC11 expression and limits EV71 replication in vitro.

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FT895, CAS 2225728-57-2

Pack Size	Availability	Price/USD
25 mg	8-10 weeks	$ 766.00
50 mg	8-10 weeks	$ 995.00
100 mg	8-10 weeks	$ 1,560.00
1 mL * 10 mM (in DMSO)	8-10 weeks	$ 322.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

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Purity: 99.81%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	FT895 is a selective and potent HDAC11 inhibitor with antifungal and antitumor activity that inhibits HDAC11 expression and limits EV71 replication in vitro.
Targets&IC50	HDAC11:3 nM
In vitro	FT895 is a highly selective inhibitor of HDAC11, exhibiting over 1000-fold selectivity against the other 10 members of the HDAC family[1].

Molecular Weight	352.31
Formula	C16H15F3N4O2
CAS No.	2225728-57-2

Storage

store at low temperature

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 20 mg/mL (56.77 mM), Sonication is recommended.

References and Literature

1. Martin MW, et al. Discovery of novel N-hydroxy-2-arylisoindoline-4-carboxamides as potent and selective inhibitors of HDAC1Bioorg Med Chem Lett. 2018 Jul 1;28(12):2143-2147.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

FT895 2225728-57-2 Chromatin/Epigenetic DNA Damage/DNA Repair Microbiology/Virology HDAC Antifungal FT 895 FT-895 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.