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FT895

FT895
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Purity:99.81%
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FT895

Catalog No. T11329Cas No. 2225728-57-2
FT895 is a selective and potent HDAC11 inhibitor with antifungal and antitumor activity, inhibiting HDAC11 expression and limiting EV71 replication in vitro (in vitro).
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
25 mg$7668-10 weeks
50 mg$9958-10 weeks
100 mg$1,5608-10 weeks
1 mL x 10 mM (in DMSO)$3228-10 weeks
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Product Introduction

Bioactivity
Description
FT895 is a selective and potent HDAC11 inhibitor with antifungal and antitumor activity, inhibiting HDAC11 expression and limiting EV71 replication in vitro (in vitro).
Targets&IC50
HDAC11:3 nM
In vitro
FT895 is a highly selective inhibitor of HDAC11, exhibiting over 1000-fold selectivity against the other 10 members of the HDAC family[1].
Chemical Properties
Molecular Weight352.31
FormulaC16H15F3N4O2
Cas No.2225728-57-2
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 20 mg/mL (56.77 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.8384 mL14.1920 mL28.3841 mL141.9205 mL
5 mM0.5677 mL2.8384 mL5.6768 mL28.3841 mL
10 mM0.2838 mL1.4192 mL2.8384 mL14.1920 mL
20 mM0.1419 mL0.7096 mL1.4192 mL7.0960 mL
50 mM0.0568 mL0.2838 mL0.5677 mL2.8384 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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