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Fuziline
Catalog No. T3S0631Cas No. 80665-72-1
Fuziline is a diterpene alkaloid found in Aconitum kusnezoffii and Aconitum carmichaelii.It is functionally related to an aconitane.
Fuziline
Catalog No. T3S0631Cas No. 80665-72-1
Fuziline is a diterpene alkaloid found in Aconitum kusnezoffii and Aconitum carmichaelii.It is functionally related to an aconitane.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $37 | In Stock | |
| 5 mg | $58 | In Stock | |
| 10 mg | $94 | In Stock | |
| 25 mg | $157 | In Stock | |
| 50 mg | $232 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $76 | In Stock |
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Purity:99.96%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Fuziline is a diterpene alkaloid found in Aconitum kusnezoffii and Aconitum carmichaelii.It is functionally related to an aconitane. |
| In vitro | In the in vitro assays,fuziline increases cell viability in the model of ISO‐induced injury. |
| Cell Research | Rat cardiomyocytes(H9c2）were cultured in 96-well plates with High‐glucose DMEM added with 10% FBS,100 μg/mL streptomycin and 100 U/mL penicillin,and H9c2 cells were placed in an incubator with 37°C and 5% CO2 for 24 hours. then addressed with isoproterenol(ISO) and different concentrations of fuziline for the indicated time. Then, the DMEM was removed and 100 μL MTT solution (0.1 mg/well) was added, and H9c2 cells were incubated for 3 hours. After that, the supernatant was removed and the formazan crystals were dissolved in 150 μL DMSO. Then, the absorbance of each sample was detected at 490 nm by a microplate reader.[2] |
| Molecular Weight | 453.57 |
| Formula | C24H39NO7 |
| Cas No. | 80665-72-1 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (110.24 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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