Shopping Cart
- Remove All
Your shopping cart is currently empty
GSK 3008348 hydrochloride
Catalog No. T15583Cas No. 1629249-40-6
Alias GSK-3008348 hydrochloride, GSK3008348 hydrochloride
GSK 3008348 hydrochloride is an αvβ6 integrin inhibitor used to confirm idiopathic pulmonary fibrosis.
GSK 3008348 hydrochloride
Catalog No. T15583Alias GSK-3008348 hydrochloride, GSK3008348 hydrochlorideCas No. 1629249-40-6
GSK 3008348 hydrochloride is an αvβ6 integrin inhibitor used to confirm idiopathic pulmonary fibrosis.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $89 | Backorder | |
| 5 mg | $247 | Backorder | |
| 10 mg | $347 | Backorder | |
| 25 mg | $579 | Backorder | |
| 50 mg | $828 | Backorder | |
| 100 mg | $1,160 | Backorder |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "GSK 3008348 hydrochloride"
Bestatin hydrochloride
Cited
Ubenimex hydrochloride
T352965391-42-6
Bestatin hydrochloride (Ubenimex hydrochloride) is an inhibitor of aminopeptidase N (APN)/CD13 and aminopeptidase B.
- $47
Size
QTY
CitedTirofiban hydrochloride monohydrate
Tirofiban Hydrochloride, MK-383 Hydrochloride
T2537150915-40-5
Tirofiban（MK383） hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist.
- $40
Size
QTY
Lifitegrast
SHP-606, SAR 1118
T39771025967-78-5
Lifitegrast (SAR 1118) is an antagonist of lymphocyte function-associated antigen-1.
- $33
Size
QTY
K34c hydrochloride
K34c hydrochloride(939769-93-4 Free base)
T41151LIn house
K34c hydrochloride is an alpha5β1 integrin antagonist for glioblastoma study.
- $350
Size
QTY
ICAM-1-IN-1
T13147251994-14-6In house
ICAM-1-IN-1 is a potent and selective inhibitor of E-selectin (IC50 = 7 nM) and ICAM-1 (IC50 = 5 nM).
- $195
Size
QTY
E7820
ER68203-00
T4435289483-69-8
E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).
- $30
Size
QTY
Gantofiban
T68078183547-57-1In house
Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.
- $191
Size
QTY
Elarofiban TFA
RWJ-53308 TFA, Elarofiban TFA（198958-88-2 Free base）
T27250L198958-89-3In house
Elarofiban TFA (RWJ-53308 TFA) is a novel and orally active and selective GPIIb/IIIa antagonist for the study of cardiovascular disease.
- $195
Size
QTY
Cilengitide
Cited
EMD 121974
T2494188968-51-6
Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays) with approximately 10-fold selectivity against gpIIbIIIa.
- $45
Size
QTY
CitedTirofiban
MK383, L700462, Aggrastat
T6182144494-65-5
Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.
- $40
Size
QTY
Arg-Gly-Asp TFA (99896-85-2(free base)) Cited
RGD Trifluoroacetate, RGD
T4613
Arg-Gly-Asp TFA (99896-85-2(free base)) (RGD Trifluoroacetate) is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins.
- $35
Size
QTY
CitedSelect Batch
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | GSK 3008348 hydrochloride is an αvβ6 integrin inhibitor used to confirm idiopathic pulmonary fibrosis. |
| Targets&IC50 | ανβ5:6.9 (pIC50), αvβ6:8.4 (pIC50), ανβ8:7.7 (pIC50), ανβ3:6 (pIC50) |
| In vitro | b>METHODS: GSK 3008348 hydrochloride was subjected to fluorescence polarization assay. RESULTS: The affinity of GSK 3008348 hydrochloride for human-6 protein was 8.1 (pIC50), while its affinity in the cell adhesion assay was: 6 (pIC50) for ανβ3; 6.9 (pIC50) for ανβ5; 8.4 (pIC50) for αvβ6; and 7.7 (pIC50) for ανβ8. [1] |
| Alias | GSK-3008348 hydrochloride, GSK3008348 hydrochloride |
| Formula | C29H37N5O2 xHCl |
| Cas No. | 1629249-40-6 |
Storage & Solubility Information
| Storage | store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO: 11.66 mg/mL, Sonication and heating are recommended. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy GSK 3008348 hydrochloride | purchase GSK 3008348 hydrochloride | GSK 3008348 hydrochloride cost | order GSK 3008348 hydrochloride | GSK 3008348 hydrochloride chemical structure | GSK 3008348 hydrochloride in vitro | GSK 3008348 hydrochloride formula
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.