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HA 155

Catalog No. T22086 CAS 1229652-22-5

Synonyms: Autotaxin Inhibitor IV

HA 155 (Autotaxin Inhibitor IV) is a boronic acid-based compound, inhibiting ATX with IC50 of 5.7 nM by selectively binding to its catalytic threonine.

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HA 155, CAS 1229652-22-5

Pack Size	Availability	Price/USD
1 mg	In stock	$ 45.00
2 mg	In stock	$ 62.00
5 mg	In stock	$ 132.00
10 mg	In stock	$ 237.00
25 mg	In stock	$ 568.00
50 mg	In stock	$ 715.00
100 mg	In stock	$ 873.00

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Purity: 98.92%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	HA 155 (Autotaxin Inhibitor IV) is a boronic acid-based compound, inhibiting ATX with IC50 of 5.7 nM by selectively binding to its catalytic threonine.
Targets&IC50	ATX:5.7 nM

Synonyms	Autotaxin Inhibitor IV
Molecular Weight	463.29
Formula	C24H19BFNO5S
CAS No.	1229652-22-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: Slightly soluble

References and Literature

1. Albers H M H G , Hendrickx L J D , Van Tol R J P , et al. Structure-Based Design of Novel Boronic Acid-Based Inhibitors of Autotaxin[J]. Journal of Medicinal Chemistry, 2011, 54(13):4619-26.

Related compound libraries

This product is contained In the following compound libraries：

NO PAINS Compound Library

Related Products

Related compounds with same targets

Torbafylline BIO-32546 Thioquinapiperifil dihydrochloride Fulvic Acid Enpp-1-IN-14 FCPR03 Enpp-1-IN-16 W-7 hydrochloride

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

HA 155 1229652-22-5 Metabolism PDE inhibit Inhibitor HA-155 Phosphodiesterase (PDE) (E/Z)-HA155 Pain Cancer Autotaxin Inhibitor IV Inflammation Angiogenesis Fibrotic diseases HA155 Autotaxin inhibitor

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