Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Heclin is an inhibitor of HECT E3 ubiquitin ligase that acts by inhibiting Smurf2, Nedd4, and WWP1 with IC50 values of 6.8, 6.3, and 6.9 μM, respectively.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 39.00 | |
5 mg | In stock | $ 64.00 | |
10 mg | In stock | $ 113.00 | |
25 mg | In stock | $ 238.00 | |
50 mg | In stock | $ 378.00 | |
100 mg | In stock | $ 596.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 70.00 |
Description | Heclin is an inhibitor of HECT E3 ubiquitin ligase that acts by inhibiting Smurf2, Nedd4, and WWP1 with IC50 values of 6.8, 6.3, and 6.9 μM, respectively. |
Targets&IC50 | SMURF2:6.8 μM, Nedd4:6.3 μM, WWP1:6.9 μM |
Molecular Weight | 283.32 |
Formula | C17H17NO3 |
CAS No. | 890605-54-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (176.48 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Heclin 890605-54-6 Ubiquitination E1/E2/E3 Enzyme E1 activating enzyme Ubiquitin ligase E3 ligating enzyme Ubiquitin conjugating enzyme E2 conjugating enzyme Ubiquitin activating enzyme inhibit Inhibitor inhibitor