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NSC232003

NSC232003
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Purity:97.72%
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NSC232003

Catalog No. T12261Cas No. 1905453-18-0
NSC232003 is a highly potent and cell-permeable inhibitor of UHRF1.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$90In Stock
5 mg$223In Stock
10 mg$349In Stock
25 mg$669In Stock
50 mg$935In Stock
100 mg$1,260In Stock
500 mg$2,520In Stock
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Product Introduction

Bioactivity
Description
NSC232003 is a highly potent and cell-permeable inhibitor of UHRF1.
In vitro
NSC232003 is an effective DNA methylation inhibitor and indicate that this particular nucleotide scaffold could provide a versatile basis for the design of potent UHRF1 inhibitors.NSC232003, a uracil derivative freely available by the NCI/DTP repository, provides a versatile lead for developing highly potent and cell-permeable UHRF1 inhibitors that will enable dissection of DNA methylation inheritance.
Chemical Properties
Molecular Weight169.14
FormulaC6H7N3O3
Cas No.1905453-18-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: < 1 mg/mL (insoluble or slightly soluble)
H2O: 2 mg/mL (11.82 mM)
Solution Preparation Table
H2O
1mg5mg10mg50mg
20 mM0.2956 mL1.4781 mL2.9561 mL14.7807 mL
50 mM0.1182 mL0.5912 mL1.1825 mL5.9123 mL
100 mM0.0591 mL0.2956 mL0.5912 mL2.9561 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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