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Itaconate-alkyne

Itaconate-alkyne
Itaconate-alkyne (ITalk) is a bioorthogonal probe for quantitative, site-specific chemoproteomic profiling of itaconate in inflammatory macrophages, facilitating biochemical evaluation and proteomic analysis of its direct targets.
Catalog No. T41302Cas No. 2454181-83-8
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Purity:99.78%
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Itaconate-alkyne

Purity: 99.78%
Catalog No. T41302Alias ITalkCas No. 2454181-83-8

Itaconate-alkyne (ITalk) is a bioorthogonal probe for quantitative, site-specific chemoproteomic profiling of itaconate in inflammatory macrophages, facilitating biochemical evaluation and proteomic analysis of its direct targets.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$67In Stock
5 mg$163In Stock
10 mg$263In Stock
25 mg$538In Stock
50 mg$778In Stock
100 mg$1,090In Stock
500 mg$2,180In Stock
1 mL x 10 mM (in DMSO)$178In Stock
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Product Introduction

Bioactivity
Description
Itaconate-alkyne (ITalk) is a bioorthogonal probe for quantitative, site-specific chemoproteomic profiling of itaconate in inflammatory macrophages, facilitating biochemical evaluation and proteomic analysis of its direct targets.
In vitro
Itaconate-alkyne can capture itaconate targets including DNA damage-binding protein 1 (DDB1), Gelsolin (GSN), ATP-citrate synthase (ACLY) and Adenylate kinase 2 (AK2) in inflammatory macrophages[1].
AliasITalk
Chemical Properties
Molecular Weight238.28
FormulaC13H18O4
Cas No.2454181-83-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 245 mg/mL (1028.20 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.1967 mL20.9837 mL41.9674 mL209.8372 mL
5 mM0.8393 mL4.1967 mL8.3935 mL41.9674 mL
10 mM0.4197 mL2.0984 mL4.1967 mL20.9837 mL
20 mM0.2098 mL1.0492 mL2.0984 mL10.4919 mL
50 mM0.0839 mL0.4197 mL0.8393 mL4.1967 mL
100 mM0.0420 mL0.2098 mL0.4197 mL2.0984 mL

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