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Itaconate-alkyne

Catalog No. T41302Cas No. 2454181-83-8
Alias ITalk

Itaconate-alkyne (ITalk) is a bioorthogonal probe for quantitative, site-specific chemoproteomic profiling of itaconate in inflammatory macrophages, facilitating biochemical evaluation and proteomic analysis of its direct targets.

Itaconate-alkyne

Itaconate-alkyne

Purity: 99.78%
Catalog No. T41302Alias ITalkCas No. 2454181-83-8
Itaconate-alkyne (ITalk) is a bioorthogonal probe for quantitative, site-specific chemoproteomic profiling of itaconate in inflammatory macrophages, facilitating biochemical evaluation and proteomic analysis of its direct targets.
Pack SizePriceAvailabilityQuantity
1 mg$67In Stock
5 mg$163In Stock
10 mg$263In Stock
25 mg$538In Stock
50 mg$778In Stock
100 mg$1,090In Stock
500 mg$2,180In Stock
1 mL x 10 mM (in DMSO)$178In Stock
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Purity:99.78%
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Product Introduction

Bioactivity
Description
Itaconate-alkyne (ITalk) is a bioorthogonal probe for quantitative, site-specific chemoproteomic profiling of itaconate in inflammatory macrophages, facilitating biochemical evaluation and proteomic analysis of its direct targets.
In vitro
Itaconate-alkyne can capture itaconate targets including DNA damage-binding protein 1 (DDB1), Gelsolin (GSN), ATP-citrate synthase (ACLY) and Adenylate kinase 2 (AK2) in inflammatory macrophages[1].
AliasITalk
Chemical Properties
Molecular Weight238.28
FormulaC13H18O4
Cas No.2454181-83-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 245 mg/mL (1028.20 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.1967 mL20.9837 mL41.9674 mL209.8372 mL
5 mM0.8393 mL4.1967 mL8.3935 mL41.9674 mL
10 mM0.4197 mL2.0984 mL4.1967 mL20.9837 mL
20 mM0.2098 mL1.0492 mL2.0984 mL10.4919 mL
50 mM0.0839 mL0.4197 mL0.8393 mL4.1967 mL
100 mM0.0420 mL0.2098 mL0.4197 mL2.0984 mL

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