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JJKK 048

Catalog No. T15614 CAS 1515855-97-6

Purity 98.00% Datasheet

JJKK 048 is an ultrapotent and highly selective Monoacylglycerol lipase inhibitor.

JJKK 048, CAS 1515855-97-6

Pack Size	Availability	Price/USD
5 mg	inquiry	97.00
10 mg	inquiry	166.00
25 mg	inquiry	366.00
50 mg	inquiry	inquiry
100 mg	inquiry	inquiry

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Purity 98.00%

COA Datasheet

Biological Description

Chemical Properties

Storage & Solubility Information

Description	JJKK 048 is an ultrapotent and highly selective Monoacylglycerol lipase inhibitor.
Targets&IC50	MAGL,

Appearance	solid
Molecular Weight	434.44
Formula	C23H22N4O5
CAS No.	1515855-97-6

Storage

-20℃ 3 years powder

-80℃ 2 years in solvent

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature

1. Aaltonen N, et al. In Vivo Characterization of the Ultrapotent Monoacylglycerol Lipase Inhibitor {4-[bis-(benzo[d][1,3]dioxol-5-yl)methyl]-piperidin-1-yl}(1H-1,2,4-triazol-1-yl)methanone (JJKK-048). J Pharmacol Exp Ther. 2016 Oct;359(1):62-72. 1. Aaltonen N, et al. In Vivo Characterization of the Ultrapotent Monoacylglycerol Lipase Inhibitor {4-[bis-(benzo[d][1,3]dioxol-5-yl)methyl]-piperidin-1-yl}(1H-1,2,4-triazol-1-yl)methanone (JJKK-048). J Pharmacol Exp Ther. 2016 Oct;359(1):62-72. 2. Aaltonen N, et al. Piperazine and piperidine triazole ureas as ultrapotent and highly selective inhibitors of monoacylglycerol lipase. Chem Biol. 2013 Mar 21;20(3):379-90. 2. Aaltonen N, et al. Piperazine and piperidine triazole ureas as ultrapotent and highly selective inhibitors of monoacylglycerol lipase. Chem Biol. 2013 Mar 21;20(3):379-90.

Related Products

Related compounds with same targets

Cravatt Reagent Cravatt Reagent PF-06795071 PF-06795071 JJKK 048 JJKK 048 MAGL-IN-1 MAGL-IN-1

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Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Answers to questions you may have can be found in the Inhibitor Handling Instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.