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MAC glucuronide linker-2

Catalog No. T18231Cas No. 229977-57-5

MAC glucuronide linker-2 is an ADC linker employed in the synthesis of ADCs, offering cleavability [1].

MAC glucuronide linker-2

MAC glucuronide linker-2

Catalog No. T18231Cas No. 229977-57-5
MAC glucuronide linker-2 is an ADC linker employed in the synthesis of ADCs, offering cleavability [1].
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100 mgInquiry7-10 days
500 mgInquiry7-10 days
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Product Introduction

Bioactivity
Description
MAC glucuronide linker-2 is an ADC linker employed in the synthesis of ADCs, offering cleavability [1].
Chemical Properties
Molecular Weight455.41
FormulaC20H25NO11
Cas No.229977-57-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 200 mg/mL (439.16 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1958 mL10.9791 mL21.9582 mL109.7912 mL
5 mM0.4392 mL2.1958 mL4.3916 mL21.9582 mL
10 mM0.2196 mL1.0979 mL2.1958 mL10.9791 mL
20 mM0.1098 mL0.5490 mL1.0979 mL5.4896 mL
50 mM0.0439 mL0.2196 mL0.4392 mL2.1958 mL
100 mM0.0220 mL0.1098 mL0.2196 mL1.0979 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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