Shopping Cart
- Remove All
Your shopping cart is currently empty
MLT-748
Catalog No. T16120Cas No. 1832578-30-9
Alias MLT748, MLT 748
MLT-748 is a MALT1 allosteric inhibitor that inhibits the growth of lung cancer cells. MLT-748 acts by blocking the protein hydrolyzing activity of MALT1.
MLT-748
Catalog No. T16120Alias MLT748, MLT 748Cas No. 1832578-30-9
MLT-748 is a MALT1 allosteric inhibitor that inhibits the growth of lung cancer cells. MLT-748 acts by blocking the protein hydrolyzing activity of MALT1.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $100 | In Stock | |
| 5 mg | $247 | In Stock | |
| 10 mg | $393 | In Stock | |
| 25 mg | $588 | In Stock | |
| 50 mg | $787 | In Stock | |
| 100 mg | $1,220 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $268 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "MLT-748"
MALT1 inhibitor MI-2
MI 2 (MALT1 inhibitor), MI 2, MALT1 inhibitor
T23501047953-91-2
MI-2 (MALT1 inhibitor) is an irreversible MALT1 inhibitor.
- $31
Size
QTY
Mepazine
Pecazine
T1604060-89-9In house
Mepazine (Pecazine) is a potent and selective inhibitor of MALT1, inhibiting GSTMALT1 full length and GSTMALT1 325-760 with IC50s of 0.83 μM and 0.42 μM, respectively. Mepazine enhances apoptosis and impacts cell viability.
- $33
Size
QTY
MLT-943
MLT943
T92161832576-04-1
MLT-943 is a potent, selective, and orally active MALT1 protease inhibitor [1].
- $74
Size
QTY
JNJ-67856633
T366702230273-76-2
JNJ-67856633 is an orally active, first-in-class, potent, selective and allosteric inhibitor of MALT1 protease . JNJ-67856633 lead to tumor stasis in some cases.
- $48
Size
QTY
MIR96-IN-1
T160771311982-88-3
MIR96-IN-1 selectively inhibits biogenesis of microRNA-96, upregulating a protein target (FOXO1) and inducing apoptosis in cancer cells.
- $289
Size
QTY
Select Batch
Purity:99.62%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | MLT-748 is a MALT1 allosteric inhibitor that inhibits the growth of lung cancer cells. MLT-748 acts by blocking the protein hydrolyzing activity of MALT1. |
| Targets&IC50 | MALT1:5 nM, MALT1329-728-W580S:13 nM (Kd), MALT1329-728:42 nM (Kd) |
| In vitro | In immortalized B cells from MALT1mut/mut patients, MLT-748 (2 µM; 24 hours) increased phosphorylation levels of NF-κB signaling pathway components p65 and IκBα as early as 5 minutes after stimulation with PMA and ionomycin. |
| Alias | MLT748, MLT 748 |
| Molecular Weight | 492.32 |
| Formula | C19H19Cl2N9O3 |
| Cas No. | 1832578-30-9 |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 250 mg/mL (507.80 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy MLT-748 | purchase MLT-748 | MLT-748 cost | order MLT-748 | MLT-748 chemical structure | MLT-748 in vitro | MLT-748 formula | MLT-748 molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.