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Mal-PEG2-VCP-NB

Catalog No. T18279Cas No. 2395887-69-9

Mal-PEG2-VCP-NB is a nonclaevable ADC linker containing a Maleimide group, 2-unit PEG and a VCP NB.

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Questions

Product Introduction

Bioactivity

Description

Mal-PEG2-VCP-NB is a nonclaevable ADC linker containing a Maleimide group, 2-unit PEG and a VCP NB.

Chemical Properties

Molecular Weight	783.78
Formula	C36H45N7O13
Cas No.	2395887-69-9

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 100 mg/mL (127.59 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.2759 mL	6.3793 mL	12.7587 mL	63.7934 mL
5 mM	0.2552 mL	1.2759 mL	2.5517 mL	12.7587 mL
10 mM	0.1276 mL	0.6379 mL	1.2759 mL	6.3793 mL
20 mM	0.0638 mL	0.3190 mL	0.6379 mL	3.1897 mL
50 mM	0.0255 mL	0.1276 mL	0.2552 mL	1.2759 mL
100 mM	0.0128 mL	0.0638 mL	0.1276 mL	0.6379 mL

Calculator

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Dilution Calculator
Reconstitution Calculator
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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Mal-PEG2-VCP-NBMal PEG2 VCP NBMalPEG2VCPNBMal-PEG-2-VCP-NB