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NH2-C5-NH-Boc

Catalog No. T18617Cas No. 51644-96-3
Alias PROTAC Linker 23

NH2-C5-NH-Boc (PROTAC Linker 23) is an alkyl chain-based PROTAC linker used in the synthesis of PROTACs.

NH2-C5-NH-Boc

NH2-C5-NH-Boc

Purity: 99.14%
Catalog No. T18617Alias PROTAC Linker 23Cas No. 51644-96-3
NH2-C5-NH-Boc (PROTAC Linker 23) is an alkyl chain-based PROTAC linker used in the synthesis of PROTACs.
Pack SizePriceAvailabilityQuantity
500 mg$33In Stock
1 g$42In Stock
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Purity:99.14%
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Product Introduction

Bioactivity
Description
NH2-C5-NH-Boc (PROTAC Linker 23) is an alkyl chain-based PROTAC linker used in the synthesis of PROTACs.
In vitro
PROTACs consist of two distinct ligands connected by a linker: one targets an E3 ubiquitin ligase, and the other targets the protein of interest. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1].
AliasPROTAC Linker 23
Chemical Properties
Molecular Weight202.29
FormulaC10H22N2O2
Cas No.51644-96-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: 100 mg/mL (494.34 mM), Sonication is recommended.
Solution Preparation Table
Ethanol
1mg5mg10mg50mg
1 mM4.9434 mL24.7170 mL49.4340 mL247.1699 mL
5 mM0.9887 mL4.9434 mL9.8868 mL49.4340 mL
10 mM0.4943 mL2.4717 mL4.9434 mL24.7170 mL
20 mM0.2472 mL1.2358 mL2.4717 mL12.3585 mL
50 mM0.0989 mL0.4943 mL0.9887 mL4.9434 mL
100 mM0.0494 mL0.2472 mL0.4943 mL2.4717 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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