Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PF-06424439 is an oral and selective inhibitor of imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) (IC50 of 14 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,670.00 | |
50 mg | 6-8 weeks | $ 2,180.00 | |
100 mg | 6-8 weeks | $ 2,800.00 |
Description | PF-06424439 is an oral and selective inhibitor of imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) (IC50 of 14 nM). |
Targets&IC50 | DGAT-2:14 nM |
In vivo | PF-06424439 shows moderate clearance in rats following intravenous administration and moderate steady-state volume of distribution (Vdss) results in a short half-life[1]. |
Molecular Weight | 439.94 |
Formula | C22H26ClN7O |
CAS No. | 1469284-78-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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PF-06424439 1469284-78-3 Metabolism Transferase Acyltransferase Diglyceride acyltransferase mono- acylglycerol acyltransferase Inhibitor acyl-CoA:cholesterol acyltransferase Diacylglycerol acyltransferase PF06424439 inhibit PF 06424439 inhibitor