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RFRP-1 (human) acetate(311309-25-8 free base)

Catalog No. TP1937L1 CAS TP1937L1

RFRP-1 (human) acetate is a potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile function of isolated rat and rabbit cardiac myocytes. Reduces heart rate, stroke volume, ejection fraction and cardiac output, and increases plasma prolactin levels in rats. GnIH homolog.

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RFRP-1 (human) acetate(311309-25-8 free base) Chemical Structure

RFRP-1 (human) acetate(311309-25-8 free base), CAS TP1937L1

Pack Size	Availability	Price/USD
1 mg	In stock	$ 133.00
5 mg	In stock	$ 302.00
10 mg	In stock	$ 453.00
25 mg	In stock	$ 748.00
50 mg	In stock	$ 1,050.00
100 mg	In stock	$ 1,420.00

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Purity: 96.84%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	RFRP-1 (human) acetate is a potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile function of isolated rat and rabbit cardiac myocytes. Reduces heart rate, stroke volume, ejection fraction and cardiac output, and increases plasma prolactin levels in rats. GnIH homolog.
Targets&IC50	NPFF1:29 nM, NPFF2:0.0011 nM

Molecular Weight	1488.77
Formula	C69H105N19O16S
CAS No.	TP1937L1

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 10 mM

References and Literature

1. Gouardères et al (2006) Functional differences between NPFF1 and NPFF2 receptor coupling: high intrinsic activities of RFamide-related peptides on stimulation of [35S]GTPγS binding. Neuropharmacology 52 376 PMID: 2. Nichols et al (2010) Human RFamide-related peptide-1 diminishes cellular and integrated cardiac contractile performance. Peptides 31 2067 PMID: 3. Hinuma et al (2000) New neuropeptides containing carboxy-terminal RFamide and their receptor in mammals. Nat.Cell.Biol. 2 703 PMID:

Related compound libraries

This product is contained In the following compound libraries：

Peptide Compound Library Bioactive Compounds Library Max Neurotransmitter Receptor Compound Library Bioactive Compound Library GPCR Compound Library

Related Products

Related compounds with same targets

Pancreatic Polypeptide (human) acetate SHA 68 [Leu31,Pro34]-Neuropeptide Y (porcine) L 152804 human GALP (3-32) (Leu31,Pro34)-Peptide YY (human) (TFA) BWX 46 Acetate Spexin acetate(1370290-58-6 free base)

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Keywords

RFRP-1 (human) acetate(311309-25-8 free base) TP1937L1 GPCR/G Protein Neuroscience Neuropeptide Y Receptor RFRP1 (human) acetate(311309258 free base) RFRP 1 (human) acetate(311309 25 8 free base) RFRP-1 acetate(311309-25-8 free base) inhibitor inhibit

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