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Rocastine
😃Good
Catalog No. T16778Cas No. 91833-49-7
Alias AHR-11325
Rocastine (AHR-11325) is a selective and potent non-sedating H1 receptor antagonist.
Rocastine
😃Good
Purity: 98.26%
Catalog No. T16778Alias AHR-11325Cas No. 91833-49-7
Rocastine (AHR-11325) is a selective and potent non-sedating H1 receptor antagonist.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $700 | 6-8 weeks |
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Purity:98.26%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Rocastine (AHR-11325) is a selective and potent non-sedating H1 receptor antagonist. |
| In vivo | Rocastine is effective with a 15-minute pretreatment time (PD50 = 0.13 mg/kg) as it is with a 1-hour pretreatment time (PD50 = 0.12 mg/kg). In protecting guinea pigs from collapse induced by aerosolized antigen, rocastine demonstrates approximately 36 times more potency than diphenhydramine and is as potent as oxatomide and terfenadine. At doses in vast excess (150 times) of its antihistaminic dose, rocastine does not alter the EEG of cats, nor does it potentiate yohimbine toxicity in mice[1]. |
| Alias | AHR-11325 |
| Molecular Weight | 265.37 |
| Formula | C13H19N3OS |
| Cas No. | 91833-49-7 |
| Smiles | S=C1C2=CC=CN=C2OC(CN1C)CCN(C)C |
| Relative Density. | 1.20 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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