Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SB-633825 can inhibit cancer cell growth and angiogenesis. SB-633825 is an effective and ATP-competitive inhibitor of TIE2, LOK, and BRK (IC50s: 3.5 nM, 66 nM, 150 nM, respectively).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | 5 days | $ 196.00 | |
5 mg | 5 days | $ 393.00 | |
25 mg | 6-8 weeks | $ 1,200.00 | |
50 mg | 6-8 weeks | $ 1,570.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | SB-633825 can inhibit cancer cell growth and angiogenesis. SB-633825 is an effective and ATP-competitive inhibitor of TIE2, LOK, and BRK (IC50s: 3.5 nM, 66 nM, 150 nM, respectively). |
Targets&IC50 | Brk:150 nM, LOK:66 nM, Tie2:3.5 nM |
In vitro | SB-633825 (0.1 μM) inhibits LOK to 44% maximal activity and TIE2 to 75% maximal activity. SB-633825 inhibits TIE2 Tyrosine-protein kinase, lymphocyte-oriented kinase (LOK; STK10), and breast tumor kinase (Brk; PTK6) [1]. |
Molecular Weight | 483.58 |
Formula | C28H25N3O3S |
CAS No. | 956613-01-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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SB-633825 956613-01-7 Angiogenesis Tyrosine Kinase/Adaptors BTK SB 633825 SB633825 inhibitor inhibit