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evobrutinib

Catalog No. T4387   CAS 1415823-73-2
Synonyms: MSC2364447C, M2951

Evobrutinib(M2951) , also known as M-2951 and MSC-2364447C, is a highly selective inhibitor of the Bruton's tyrosine kinase (BTK), which is important in the development and functioning of various immune cells including B -lymphocytes and macrophages. PreClinical research suggests it may be therapeutically useful in certain autoimmune diseases.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
evobrutinib Chemical Structure
evobrutinib, CAS 1415823-73-2
Pack Size Availability Price/USD Quantity
1 mg In stock $ 54.00
2 mg In stock $ 67.00
5 mg In stock $ 94.00
10 mg In stock $ 157.00
25 mg In stock $ 315.00
50 mg In stock $ 473.00
100 mg In stock $ 693.00
500 mg Inquiry $ 1,460.00
1 mL * 10 mM (in DMSO) In stock $ 94.00
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Purity: 99.42%
Purity: 98.04%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Evobrutinib(M2951) , also known as M-2951 and MSC-2364447C, is a highly selective inhibitor of the Bruton's tyrosine kinase (BTK), which is important in the development and functioning of various immune cells including B -lymphocytes and macrophages. PreClinical research suggests it may be therapeutically useful in certain autoimmune diseases.
Targets&IC50 BTK:37.9 nM
Synonyms MSC2364447C, M2951
Molecular Weight 429.51
Formula C25H27N5O2
CAS No. 1415823-73-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 55 mg/mL (128.05 mM), Sonification is recommended

TargetMolReferences and Literature

1. Crawford JJ, et al. J Med Chem. 2018, 61(6):2227-2245. 2. Li Z, et al. Drug Test Anal. 2018, doi: 10.12002/dta.2477.

Related compound libraries

This product is contained In the following compound libraries:
Tyrosine Kinase Inhibitor Library Anti-Neurodegenerative Disease Compound Library Highly Selective Inhibitor Library NO PAINS Compound Library Target-Focused Phenotypic Screening Library Covalent Inhibitor Library Angiogenesis related Compound Library Immuno-Oncology Compound Library Preclinical Compound Library ReFRAME Related Library

Related Products

Related compounds with same targets
zanubrutinib PF-06250112 BIIB068 N-piperidine Ibrutinib hydrochloride Acalabrutinib enantiomer Larotinib CP-547632 Acalabrutinib

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Keywords

evobrutinib 1415823-73-2 Angiogenesis Tyrosine Kinase/Adaptors BTK M 2951 MSC2364447C M2951 M-2951 inhibitor inhibit

 

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