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JAK3/BTK-IN-1

Catalog No. T9814   CAS 2674036-91-8

JAK3/ BTk-in-1 is a dual JAK3/BTK inhibitor that specifically targets and inhibits Janus kinase 3 (JAK3) and Bruton's tyrosine kinase (BTK), two important targets in autoimmune diseases. JAK3/ BTk-in-1 simultaneously inhibited the BTK/JAK3 signaling pathway, showing a synergistic effect. JAK3/ BTK-in-1 is a potential compound for the treatment of immune-related diseases, such as autoimmune diseases, certain types of cancer (including lymphoma and leukemia), and other diseases that may be characterized by an unbalanced immune response.

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JAK3/BTK-IN-1 Chemical Structure
JAK3/BTK-IN-1, CAS 2674036-91-8
Pack Size Availability Price/USD Quantity
25 mg 6-8 weeks $ 1,330.00
50 mg 6-8 weeks $ 1,728.00
100 mg 6-8 weeks $ 2,595.00
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Biological Description
Chemical Properties
Storage & Solubility Information
Description JAK3/ BTk-in-1 is a dual JAK3/BTK inhibitor that specifically targets and inhibits Janus kinase 3 (JAK3) and Bruton's tyrosine kinase (BTK), two important targets in autoimmune diseases. JAK3/ BTk-in-1 simultaneously inhibited the BTK/JAK3 signaling pathway, showing a synergistic effect. JAK3/ BTK-in-1 is a potential compound for the treatment of immune-related diseases, such as autoimmune diseases, certain types of cancer (including lymphoma and leukemia), and other diseases that may be characterized by an unbalanced immune response.
Molecular Weight 456.54
Formula C25H28N8O
CAS No. 2674036-91-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Guobao Zhang, et al. Pyrimidopyrroles. Patent WO2021147952A1.

Related Products

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JAK3/BTK-IN-2 BIIB068 Tolebrutinib JDB175 (±)-Zanubrutinib CP-547632 PCI-33380 MT-802

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Keywords

JAK3/BTK-IN-1 2674036-91-8 Angiogenesis Chromatin/Epigenetic JAK/STAT signaling Stem Cells Tyrosine Kinase/Adaptors JAK BTK JAK3/BTK IN 1 JAK-3/BTK-IN-1 JAK3/BTKIN1 inhibitor inhibit

 

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