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SEC inhibitor KL-2

SEC inhibitor KL-2
SEC inhibitor KL-2 (KL-2) is a potent and selective inhibitor of the super elongation complex (SEC), showing a dose-dependent inhibitory effect on the AFF4-CCNT1 interaction with a Ki of 1.50 μM.
Catalog No. T16868Cas No. 900308-51-2
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Purity:98.03%
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SEC inhibitor KL-2

Purity: 98.03%
Catalog No. T16868Alias KL-2Cas No. 900308-51-2

SEC inhibitor KL-2 (KL-2) is a potent and selective inhibitor of the super elongation complex (SEC), showing a dose-dependent inhibitory effect on the AFF4-CCNT1 interaction with a Ki of 1.50 μM.
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Pack SizePriceAvailabilityQuantity
1 mg$48In Stock
5 mg$137In Stock
10 mg$227In Stock
25 mg$347In Stock
50 mg$521In Stock
100 mg$798In Stock
200 mg$1,070In Stock
1 mL x 10 mM (in DMSO)$115In Stock
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Product Introduction

Bioactivity
Description
SEC inhibitor KL-2 (KL-2) is a potent and selective inhibitor of the super elongation complex (SEC), showing a dose-dependent inhibitory effect on the AFF4-CCNT1 interaction with a Ki of 1.50 μM.
AliasKL-2
Chemical Properties
Molecular Weight333.74
FormulaC17H13ClFNO3
Cas No.900308-51-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 75.0 mg/mL (224.7 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9963 mL14.9817 mL29.9634 mL149.8172 mL
5 mM0.5993 mL2.9963 mL5.9927 mL29.9634 mL
10 mM0.2996 mL1.4982 mL2.9963 mL14.9817 mL
20 mM0.1498 mL0.7491 mL1.4982 mL7.4909 mL
50 mM0.0599 mL0.2996 mL0.5993 mL2.9963 mL
100 mM0.0300 mL0.1498 mL0.2996 mL1.4982 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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