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SR 2640 hydrochloride

SR 2640 hydrochloride
SR 2640 hydrochloride is a competitive antagonist of leukotriene D4 and E4 and can be used in studies about leukotrienes in human asthma.
Catalog No. T23390Cas No. 146662-42-2
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Purity:98.36%
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SR 2640 hydrochloride

Catalog No. T23390Cas No. 146662-42-2
SR 2640 hydrochloride is a competitive antagonist of leukotriene D4 and E4 and can be used in studies about leukotrienes in human asthma.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$41In Stock
5 mg$97In Stock
10 mg$147In Stock
25 mg$297In Stock
50 mg$478In Stock
100 mg$689In Stock
500 mg$1,480In Stock
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Product Introduction

Bioactivity
Description
SR 2640 hydrochloride is a competitive antagonist of leukotriene D4 and E4 and can be used in studies about leukotrienes in human asthma.
In vivo
In Guinea pigs, intravenous injection of SR2640 (1 mg/kg) prevents the contractile responses of the ileum and trachea to leukotriene D4 and E4[1].
Chemical Properties
Molecular Weight406.86
FormulaC23H19ClN2O3
Cas No.146662-42-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 225.0 mg/mL (553.0 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4578 mL12.2892 mL24.5785 mL122.8924 mL
5 mM0.4916 mL2.4578 mL4.9157 mL24.5785 mL
10 mM0.2458 mL1.2289 mL2.4578 mL12.2892 mL
20 mM0.1229 mL0.6145 mL1.2289 mL6.1446 mL
50 mM0.0492 mL0.2458 mL0.4916 mL2.4578 mL
100 mM0.0246 mL0.1229 mL0.2458 mL1.2289 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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