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Sodium Channel inhibitor 2

Catalog No. T12951 CAS 653573-60-5

Sodium Channel inhibitor 2 is a blocker of sodium channel.

Sodium Channel inhibitor 2, CAS 653573-60-5

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Purity 98.00%

Datasheet

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Sodium Channel inhibitor 2 is a blocker of sodium channel.
Targets&IC50	Sodium channel,
In vitro	Sodium Channel inhibitor 2 is a sodium channel blocker ,and is useful for the treatment of neuronal damage following global and focal ischemia and for the treatment or prevention of neurodegenerative conditions(amyotrophic lateral sclerosis).

Molecular Weight	466.4
Formula	C26H25Cl2N3O
CAS No.	653573-60-5

Storage

-20℃ 3 years powder

-80℃ 2 years in solvent

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature

1. Sun Qun, et al. Preparation of aryl-substituted benzimidazoles and their use as sodium channel blockers. WO 2004011439 A2.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Tech Support

Answers to questions you may have can be found in the Inhibitor Handling Instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.