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Sunset Yellow FCF

Catalog No. TN2245   CAS 2783-94-0
Synonyms: Food Yellow 3, Orange Yellow S, Sunset yellow, CI 15985

Sunset Yellow FCF (Sunset yellow) is an orange azo dye with pH-dependent absorbance.Sunset Yellow FCF is used in food, cosmetics and pharmaceuticals.It is used as a colorant food additive in many food products.They may be cytotoxic and genotoxic, so care must be taken when using these materials as food additives.

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Sunset Yellow FCF Chemical Structure
Sunset Yellow FCF, CAS 2783-94-0
Pack Size Availability Price/USD Quantity
100 mg In stock $ 41.00
500 mg In stock $ 85.00
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Purity: 98.03%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Sunset Yellow FCF (Sunset yellow) is an orange azo dye with pH-dependent absorbance.Sunset Yellow FCF is used in food, cosmetics and pharmaceuticals.It is used as a colorant food additive in many food products.They may be cytotoxic and genotoxic, so care must be taken when using these materials as food additives.
In vitro Sunset Yellow FCF (250 μg/ml) reduces the LPS-induced proliferation of isolated mouse splenocytes, as well as inhibits the proliferation of isolated mouse splenocytes in an allogeneic mixed lymphocyte reaction.[3]
In vivo Sunset yellow FCF (0.325 mg/kg; mice) induces chromosomal aberrations in somatic and germ cells and morphological abnormalities in sperm in mice, but it is not genotoxic in a micronucleus gut assay in mice when administered at doses up to 2,000 mg/kg.[4]
Synonyms Food Yellow 3, Orange Yellow S, Sunset yellow, CI 15985
Molecular Weight 454.39
Formula C16H12N2Na2O7S2
CAS No. 2783-94-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 90.0 mg/mL (199.0 mM), Sonication is recommended.

DMSO: 90 mg/mL (198.95 mM)

TargetMolReferences and Literature

1. Kus E, et al. Genotoxic and cytotoxic effects of Sunset Yellow and Brilliant Blue, colorant food additives, on human blood lymphocytes.Pak J Pharm Sci. 2015 Jan;28(1):227-30. 2. Ghoneim M M, et al. Electro-Fenton oxidation of Sunset Yellow FCF azo-dye in aqueous solutions. Desalination, 2011, 274(1-3): 22-30. 3. Yadav A, et al. Sunset yellow FCF, a permitted food dye, alters functional responses of splenocytes at non-cytotoxic dose. Toxicol Lett. 2013;217(3):197-204. 4. Sayed HM, et al. The modifying effect of selenium and vitamins A, C, and E on the genotoxicity induced by sunset yellow in male mice. Mutat Res. 2012;744(2):145-153.

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Keywords

Sunset Yellow FCF 2783-94-0 Endocrinology/Hormones Androgen Receptor CI-15985 Food Yellow 3 CI15985 Orange Yellow S Sunset yellow CI 15985 inhibitor inhibit

 

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