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SK33
Catalog No. T12928Cas No. 1928724-23-5
SK33 is a potent and tissue selective anti-androgen agent. SK33 reduces androgen receptor (AR) transcriptional activity.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $123 | In Stock | |
| 5 mg | $263 | In Stock | |
| 10 mg | $396 | In Stock | |
| 25 mg | $665 | In Stock | |
| 50 mg | $947 | In Stock | |
| 100 mg | $1,280 | In Stock | |
| 500 mg | $2,570 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $332 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | SK33 is a potent and tissue selective anti-androgen agent. SK33 reduces androgen receptor (AR) transcriptional activity. |
| In vitro | SK33 has a significantly potent activity (IC50:0.2 μM) in LNCaPAR+ cells. SK33 decreases cells enter S-phase in LNCaP cells. In LNCaP/BicR cells, increasing concentrations of SK33 for 96 hours results in a dose-dependent response and an inhibition of cell growth(IC50 : 5 μM for SK33). |
| In vivo | AR transcriptional activity inhibited by SK33 after 50 mg/kg treatment for 24 hours. |
| Molecular Weight | 500.31 |
| Formula | C20H13F9N2O3 |
| Cas No. | 1928724-23-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/mL (109.93 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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