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Telekin

Catalog No. T9144 CAS 6752-90-5

Telekin, a eudesmane-type sesquiterpene lactone compound isolated from Chinese folk medicine Carpesium divaricatum, has been reported to strongly inhibit the proliferation of cancer cells

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Telekin, CAS 6752-90-5

Pack Size	Availability	Price/USD
1 mg	In stock	$ 133.00
5 mg	In stock	$ 302.00
10 mg	In stock	$ 453.00
25 mg	In stock	$ 747.00
50 mg	In stock	$ 1,050.00
1 mL * 10 mM (in DMSO)	In stock	$ 276.00

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Purity: 99.97%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Telekin, a eudesmane-type sesquiterpene lactone compound isolated from Chinese folk medicine Carpesium divaricatum, has been reported to strongly inhibit the proliferation of cancer cells
In vitro	telekin activates the mitochondria-mediated apoptotic pathway in hepatocellular carcinoma cells and may merit further investigation as a potential therapeutic agent for the treatment of hepatocellular carcinoma[1].

Molecular Weight	248.32
Formula	C15H20O3
CAS No.	6752-90-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 27.5 mg/ml (110.74 mM)

References and Literature

1. Zheng B , Wu L , Ma L , et al. Telekin induces apoptosis associated with the mitochondria-mediated pathway in human hepatocellular carcinoma cells[J]. Biological & Pharmaceutical Bulletin, 2013, 36(7):1118. 2. Li L , Zheng B B , Ma L S , et al. Telekin suppresses human hepatocellular carcinoma cells in vitro by inducing G2/M phase arrest via the p38 MAPK signaling pathway[J]. Acta Pharmacologica Sinica, 2014, 35(10):1311-1322.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Active Compound Library Traditional Chinese Medicine Monomer Library Natural Product Library Tibetan medicine Compound Library RO5 Drug-like Natural Product Library Natural Product Library for HTS Chinese Pharmacopoeia Natural Product Library Traditional Mongolian Medicine Compound Library Anti-Cancer Compound Library Selected Plant-Sourced Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Telekin 6752-90-5 Others HepG-2 Carpesium divaricatum inhibit Apoptosis Inhibitor anticancer sesquiterpene lactone inhibitor

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