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Tuna AI acetate

Tuna AI acetate
Tuna AI acetate is an inhibitor of angiotensin-converting enzyme (ACE) in non-competitive manner derived from tuna muscle.
Catalog No. T24906L
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Purity:98.49%
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Tuna AI acetate

Catalog No. T24906L

Tuna AI acetate is an inhibitor of angiotensin-converting enzyme (ACE) in non-competitive manner derived from tuna muscle.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$117In Stock
2 mg$165In Stock
5 mg$262In Stock
10 mg$388In Stock
25 mg$592In Stock
50 mg$828In Stock
100 mg$1,110In Stock
200 mg$1,480In Stock
1 mL x 10 mM (in DMSO)$460In Stock
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Product Introduction

Bioactivity
Description
Tuna AI acetate is an inhibitor of angiotensin-converting enzyme (ACE) in non-competitive manner derived from tuna muscle.
Targets&IC50
Hippuryl-L-histidyl-L-leucine:1.7 μM(rabbit lung ACE), Ang I:5.7 μM(rabbit lung ACE)
In vitro
Tuna AI acetate inhibited rabbit lung ACE non-competitively with Ki values of 1.7 and 5.7 microM with substrates, hippuryl-L-histidyl-L-leucine and angiotensin I, respectively. Tuna AI acetate (5.3 microM) also doubled the effect of bradykinin in the contraction of isolated guinea pig ileum[1].
Chemical Properties
Molecular Weight1013.1
FormulaC46H68N12O14
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 22.5 mg/mL (22.21 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM0.9871 mL4.9353 mL9.8707 mL49.3535 mL
5 mM0.1974 mL0.9871 mL1.9741 mL9.8707 mL
10 mM0.0987 mL0.4935 mL0.9871 mL4.9353 mL
20 mM0.0494 mL0.2468 mL0.4935 mL2.4677 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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