Powder: -20°C for 3 years | In solvent: -80°C for 1 year
XY101 is a selective, metabolically stable and orally available agonist of RORγ inverse(IC50 of 30 nM and a Kd of 380 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 135.00 | |
5 mg | In stock | $ 289.00 | |
10 mg | In stock | $ 497.00 | |
25 mg | In stock | $ 793.00 | |
50 mg | In stock | $ 1,130.00 | |
100 mg | In stock | $ 1,520.00 | |
500 mg | In stock | $ 2,970.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 359.00 |
Description | XY101 is a selective, metabolically stable and orally available agonist of RORγ inverse(IC50 of 30 nM and a Kd of 380 nM). |
Targets&IC50 | RORγ:(kd)380 nM , RORγ:30 nM |
In vitro | XY101 effectively inhibits cell growth, colony formation and expression of androgen receptor (AR), AR-V7 and prostate specific antigen (PSA)[1]. |
In vivo | XY101 demonstrates substantial antitumor effects, including inhibition of tumor growth, throughout the treatment period and is well-tolerated, evidenced by the absence of significant body weight loss[1]. |
Molecular Weight | 563.48 |
Formula | C25H20F7NO4S |
CAS No. | 2349368-16-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 225 mg/mL (399.3 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
XY101 2349368-16-5 Metabolism ROR XY-101 XY 101 inhibitor inhibit