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AGX51 is an antagonist of inhibitor of DNA binding (ID) proteins. AGX51 treatment lead to pan-Id degradation, cell cycle arrest, and cell death.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | 112 € | In Stock | |
5 mg | 276 € | In Stock | |
10 mg | 434 € | In Stock | |
25 mg | 688 € | In Stock | |
50 mg | 945 € | In Stock | |
100 mg | 1.311 € | In Stock | |
1 mL x 10 mM (in DMSO) | 303 € | In Stock |
Description | AGX51 is an antagonist of inhibitor of DNA binding (ID) proteins. AGX51 treatment lead to pan-Id degradation, cell cycle arrest, and cell death. |
In vitro | AGX51 inhibits the Id1-E47 interaction. AGX51 is well-tolerated in mice and phenocopies the genetic loss of Id expression in AMD and ROP models by inhibiting retinal neovascularization. AGX51 may have utility in the management of multiple diseases[1]. |
Molecular Weight | 431.52 |
Formula | C27H29NO4 |
Cas No. | 330834-54-3 |
Smiles | CCC(=O)N(CCC(c1ccc2OCOc2c1)c1ccccc1OC)Cc1ccccc1 |
Relative Density. | 1.169 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | Ethanol: 95 mg/mL (220.15 mM), Sonication is recommended. DMSO: 95 mg/mL (220.15 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
Ethanol/DMSO
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