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Alkynyl Palmitic Acid is an alkyl chain-based PROTAC linker that can be used in PROTAC synthesis.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $122 | In Stock | |
5 mg | $372 | In Stock | |
50 mg | $1,150 | In Stock | |
1 mL x 10 mM (in DMSO) | $318 | In Stock |
Description | Alkynyl Palmitic Acid is an alkyl chain-based PROTAC linker that can be used in PROTAC synthesis. |
In vitro | PROTACs, or proteolysis-targeting chimeras, are composed of two distinct ligands joined by a linker. One of these ligands binds to a specific protein target, while the other binds to an E3 ubiquitin ligase. When the PROTAC binds to both the target protein and the E3 ligase, it triggers the ubiquitin-proteasome system within cells to degrade the target protein, thereby providing a mechanism for targeted protein degradation. |
Molecular Weight | 252.39 |
Formula | C16H28O2 |
Cas No. | 99208-90-9 |
Smiles | C(CCCCCCCCC#C)CCCCC(O)=O |
Relative Density. | 0.9310 g/cm3 (Estimated) |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 100 mg/mL (396.21 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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