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Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | $475 | 35 days | |
50 mg | $1,990 | 35 days |
Description | AM12 inhibits Lanthanide-evoked TRPC5 activity (IC50: 0.28 μM). |
In vitro | AM12 also inhibits TRPC5 activity evoked by the agonist (-)-Englerin A. AM12 also inhibits TRPC4 channels similarly. AM12 inhibits TRPC5 and TRPC4 channels via a site accessible from the extracellular face of the membrane, acting directly on either the channel or a site closely associated with it. AM12 also inhibits Ca2+ entry evoked by Gd3+. AM12 inhibits the Gd3+-evoked Ca2+ signal (IC50: 0.28 μM). AM12 is slightly more potent than the natural product Galangin as an inhibitor of the Gd3+-evoked signal. |
Molecular Weight | 349.13 |
Formula | C15H9BrO5 |
Cas No. | 2387510-84-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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