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Anti-inflammatory agent 49
🥰Excellent
Catalog No. T83057Cas No. 851471-44-8
Anti-inflammatory agent 49 is a potent inhibitor of Drp1-Fis1 interaction, inhibits GTPase, and can be used in the study of diseases caused by mitochondrial dysfunction.
Anti-inflammatory agent 49
🥰Excellent
Purity: 99.74%
Catalog No. T83057Cas No. 851471-44-8
Anti-inflammatory agent 49 is a potent inhibitor of Drp1-Fis1 interaction, inhibits GTPase, and can be used in the study of diseases caused by mitochondrial dysfunction.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $88 | In Stock | |
| 5 mg | $213 | In Stock | |
| 10 mg | $347 | In Stock | |
| 25 mg | $695 | In Stock | |
| 50 mg | $1,090 | In Stock | |
| 100 mg | $1,480 | In Stock |
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Purity:99.74%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Anti-inflammatory agent 49 is a potent inhibitor of Drp1-Fis1 interaction, inhibits GTPase, and can be used in the study of diseases caused by mitochondrial dysfunction. |
| In vitro | In H9c2 cells, the anti-inflammatory agent 49 (2 µM; 16 hours) reduced the percentage of cells with fragmented mitochondria. The percentage of fragmented cells decreased from 22% (LPS + Veh) to 9% (LPS + SC9), compared to 4% in the absence of LPS[1]. |
| In vivo | The anti-inflammatory agent 49 (10 mg/kg, every 8 hours for 72 hours) effectively treats endotoxemia induced by LPS in mice [1]. |
| Molecular Weight | 466.52 |
| Formula | C21H22N8O3S |
| Cas No. | 851471-44-8 |
| Smiles | O=C1NC(=O)N(C(N)=C1N(C(=O)CSC=2N=C3N=C(C=C(N3N2)C)C)C)CC=4C=CC=CC4 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (171.48 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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