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ML-097
Catalog No. T21970Cas No. 743456-83-9
ML-097 (CID-2160985) is a universal activator of Ras-related GTPases.
ML-097
Catalog No. T21970Cas No. 743456-83-9
ML-097 (CID-2160985) is a universal activator of Ras-related GTPases.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $59 | In Stock | |
| 10 mg | $87 | In Stock | |
| 25 mg | $143 | In Stock | |
| 50 mg | $213 | In Stock | |
| 100 mg | $318 | In Stock | |
| 500 mg | $763 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $65 | In Stock |
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Purity:99.12%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | ML-097 (CID-2160985) is a universal activator of Ras-related GTPases. |
| In vitro | Activators of Cdc42 function might have a beneficial function in solid tumors and ameliorate faciogenital dysplasia where Cdc42 GEF is mutant. Rho GTPases affect cell proliferation and migration (11). In some cases underexpression is associated with cancer[1]. |
| In vivo | Rac2 is selectively expressed in immune cells and human Rac2 mutations result in immunodeficiency. Therefore, activators of Rac2 or other Rac family members might be of benefit in these diseases. Rac1 is important for maintaining hair follicle integrity and a rac1 deficiency in the skin causes nearly complete hair loss in an animal model[1]. |
| Molecular Weight | 307.139 |
| Formula | C14H11BrO3 |
| Cas No. | 743456-83-9 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
| Solubility Information | DMSO: 4 mg/mL (13.03 mM) | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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